Postdoctoral position at the Institute of Cell Biology in Düsseldorf
How do adhesion G protein-coupled receptors translate signals into function
Project description:
The Institute of Cell Biology focuses on understanding Adhesion G protein-coupled receptors (aGPCRs) and how they translate signals into function. Adhesion GPCRs form the second largest class of GPCRs and are highly essential in health and disease, rendering them promising drug targets. It has become increasingly clear that they are essential players in various biological processes, especially in metabolism regulation. However, for many of them their specific roles in this context are poorly understood. The group of Simone Prömel in Düsseldorf aims to provide a mechanistic link between their signalling capacities and their physiological impact.
Your tasks:
• Experimental work to study Adhesion GPCRs in physiological processes, in particular in various metabolic processes by using animal models as well as molecular and cell biology techniques
• Analyses of cellular signal transduction of Adhesion GPCRs
• Organisation, planning, establishment, performance of experiments and data analysis
• Presentation of data in publications and on conferences
• Participation in acquisition of third-party funding
• Teaching and training/supervision of undergraduate and PhD students
Requirements:
• PhD in biology, biochemistry or equivalent natural or life sciences
• Background in molecular biology and cell biology techniques
• Experience in working with the model organisms mouse
• Experience in publishing in international journals
• Excellent English communication skills (written and oral)
• Experience in writing grant applications for third-party funding is advantageous
• Knowledge in receptor biology and a strong interest in biochemical and physiological questions are advantageous
• High level of motivation, excellent organisation skills and the ability to work independently and in a team